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ChemicalBook >> CAS DataBase List >> [2H3]-Quinidine

[2H3]-Quinidine

[2H3]-Quinidine price.
  • $185 - $1455
  • Product name: [2H3]-Quinidine
  • CAS: 1267657-68-0
  • MF: C20H24N2O2
  • MW: 324.42
  • EINECS:
  • MDL Number:MFCD09841218
  • Synonyms:[2H3]-Quinidine;(S)-[(2R,4S,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl][6-(2H?)methoxyquinolin-4-yl]methanol
Price3 Properties Safety Information Description
3 prices
Selected condition：
Brand
  • Cayman Chemical
  • TRC
Package
  • 2.5mg
  • 25mg
  • ManufacturerCayman Chemical
  • Product number28884
  • Product descriptionQuinidine-d3
  • Packaging2.5mg
  • Price$335
  • Updated2024-03-01
  • Buy
  • ManufacturerTRC
  • Product numberQ685002
  • Product descriptionQuinidine-d3
  • Packaging2.5mg
  • Price$185
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberQ685002
  • Product descriptionQuinidine-d3
  • Packaging25mg
  • Price$1455
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Cayman Chemical 28884 Quinidine-d3 2.5mg $335 2024-03-01 Buy
TRC Q685002 Quinidine-d3 2.5mg $185 2021-12-16 Buy
TRC Q685002 Quinidine-d3 25mg $1455 2021-12-16 Buy

Properties

storage temp. :Store at -20°C
solubility :Chloroform: slightly soluble; Methanol: slightly, heated
form :A solid

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P321 Specific treatment (see … on this label).
P330 Rinse mouth.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Quinidine-d3 is intended for use as an internal standard for the quantification of quinidine by GC- or LC-MS. Quinidine is a stereoisomer of the antimalarial agent quinine and a class Ia antiarrhythmic agent.1,2 Quinidine blocks the voltage-gated sodium (Nav) channel Nav1.5 in a use-dependent manner.1 It decreases the amplitude and duration of action potentials in isolated canine ventricular myocytes.3 Quinidine inhibits KKr, peak INa, and late INa (IC50s = 4.5, 11, and 12 μM, respectively) and can induce torsade de pointes in isolated rabbit hearts when used at a concentration of 1 μM.2 It induces QT prolongation in dogs.4 Quinidine also binds to M2 muscarinic acetylcholine receptors (Ki = 7.5 μM for human recombinant receptors expressed in HM2-B10 cells).5 Formulations containing quinidine have been used in the treatment of atrial fibrillation and ventricular arrhythmias.

Suppliers and manufacturers

TargetMol Chemicals Inc.
Quinidine-d3
$449.00 /1mg
Quinidine-d3 CAS:1267657-68-0
Artis Biotech Co. Ltd. Shanghai EFE Biological Technology Co., Ltd. Shanghai Hongye Biotechnology Co. Ltd ChemeGen(Shanghai) Biotechnology Co.,Ltd. Hubei Xinyang Medical Technology Co., Ltd Energy Chemical QUALITY CONTROL SOLUTIONS LTD. PureChemland Co.,Ltd. TargetMol Chemicals Inc.